Fluoxetine (Prozac), is a common prescription SSRI medication used in the treatment of anxiety and depression.
There’s a moderate risk of CBD interacting with fluoxetine. There are two main ways CBD can interact with Prozac:
Slowed elimination and increased effect.
Adverse effects from mixing CBD with Prozac include nausea, diarrhea, and headaches.
Before taking CBD and Prozac together, you must consult with your physician first. They may want to reduce your dose of Prozac or advise you to separate your dose of SSRIs and CBD by about 2-hours to minimize your risk.