Low doses of CBD are generally considered safe to use with alprazolam (Xanax). However, you should always speak with your prescribing physician about combining CBD or any supplements alongside alprazolam. Other factors or medications could contraindicate the use of CBD.
It’s also not a good idea to use large doses of CBD, THC, or other cannabinoids alongside alprazolam or other benzodiazepine.
When used in conjunction with psychotropic medicines like alprazolam (Xanax), CBD may cause moderate to severe risk of negative interactions or side effects.
The main issue with this combination is that CBD interferes or slows the metabolism of alprazolam, thus increasing the chances for side effects to occur.
CBD and alprazolam may exhibit compounded effects towards the sedative, muscle-relaxant, and hypotensive effects. Both substances exert a similar influence in these areas and may cause side effects from causing too strong of a push in this direction.
Side effects of this interaction would include dizziness, lightheadedness, fatigue, and fainting.
Patients need to exercise caution and should only take these medicines together under the close monitoring of a physician.